研究团队围绕高灵敏度功能核酸探针的构建及重大疾病标志物的定量分析开展研究，建立了聚合物电化学发光信号放大探针，实现了传染病病原体实时监测及普适性标志物检测(ACS Central Science, IF=18.728; Theranostics, IF=11.600; Nature Protocols, IF=17.021; Sensors & Actuators: B. Chemical, IF=9.221, ESI高被引、热点论文)；设计了结核结节特异的功能核酸探针，达到了单结核结节影像诊断及结核病协同纳米治疗的目的(ACS Nano、2篇, IF=18.027; Journal of Controlled Release, IF=11.467, ESI高被引、热点论文; ACS Applied Materials & Interfaces, IF= 10.383)；构建了靶标触发的功能核酸探针，应用于病灶在体成像诊断及高灵敏度液体活检新模式(Bioactive Materials, IF=16.874, ESI高被引; ACS Nano, IF=18.027; Small、2篇, IF=15.153; ACS Applied Materials & Interfaces, IF= 10.383)。已发表论文26篇，其中IF>10的12篇，ESI热点论文2篇，ESI高被引论文3篇， SCI一区论文21篇，他引1000次以上，单篇引用最高134次，H指数为21，i10指数为28；主持国家重点研发计划1项，国家自然科学基金项目3项，广东省自然科学基金杰出青年项目1项，南方医科大学高层次人才科研启动项目1项、国家杰出青年/优秀青年科学基金培育计划1项，申请国家发明专利26项、授权12项。任中国中西医学会传染病专业委员会青年委员，中国检验装备学会检验医学分会委员，广东省青年科学家协会会员，广东省医学会放射医学分会分子影像学组委员，广东省精准医学应用学会皮肤性病分会常务委员。

代表性论文

1) Yuhui Liao (第一作者), Zhijin Fan, Huaping Deng, Yang Yang, Jingyan Lin, Zhaoyan Zhao, Qingqin Tan, Bin Li, Xi Huang*. Zika Virus Liquid Biopsy: a Dendric Ru(bpy)32+-Polymer Amplified ECL Diagnosis Strategy Using a Drop of Blood. ACS Central Science. 2018, 4, 1403-1411 (SCI indexed, IF= 18.728; 化学一区)

2) Bin Li#, Wei Wang#, Lu Zhao#, Dingyuan Yan#, Xiaoxue Li, Qiuxia Gao, Judun Zheng, Sitong Zhou, Shanshan Lai, Yi Feng, Jie Zhang, Hang Jiang, Chengmin Long, Wenjun Gan, Xiaodong Chen*, Dong Wang*, Ben Zhong Tang*, Yuhui Liao*(末位通讯). Multifunctional AIE Nanosphere-Based “Nanobomb” for Trimodal Imaging-Guided Photothermal/Photodynamic/Pharmacological Therapy of Drug-Resistant Bacterial Infections. ACS Nano. 2023, 17, 4601−4618 (SCI indexed, IF=18.027; 工程技术一区)

3) Yuhui Liao#(共同第一), Bin Li#, Zheng Zhao#, Yu Fu, Qingqin Tan, Xingyu Li, Wei Wang, Jialing Yin, Hong Shan*, Ben Zhong Tang*, Xi Huang*. Targeted Theranostics for Tuberculosis: A Rifampicin-Loaded Aggregation-Induced Emission Carrier for Granulomas-Tracking and Anti-Infection. ACS Nano. 2020, 14, 8046-8058 (SCI indexed, IF= 18.027; 工程技术一区)

4) Zhijin Fan#, Yichao Wang#, Lanqing Li#, Fanchu Zeng, Qiuping Shang, Yuhui Liao*(共同通讯), Changhong Liang*, and Liming Nie*. Tumor-Homing and Immune-Reprogramming Cellular Nanovesicles for Photoacoustic Imaging Guided Phototriggered Precise ChemoImmunotherapy. ACS Nano. 2022, 16, 16177-16190 (SCI indexed, IF= 18.027; 工程技术一区)

5) Zhijin Fan#, Hongxing Liu#, Yaohua Xue, Jingyan Lin, Yu Fu, Zhaohua Xia, Dongming Pan, Jian Zhang*, Kun Qiao*, Zhenzhen Zhang & Yuhui Liao*(末位通讯). Reversing Cold Tumors to Hot: a Immunoadjuvant-functionalized Metal-organic Framework for Multimodal Imaging-guided Synergistic Photo-immunotherapy. Bioactive Materials. 2021, 6, 312-325. (SCI indexed, IF= 16.874, 工程技术一区，ESI高被引)

6) Zhisheng Ji#, Judun Zheng#, Yanming Ma#, Hongyi Lei#, Weiqiang Lin, Jialin Huang, Hua Yang, Guowei Zhang, Bin Li, Bowen Shu, Xianjin Du*, Jian Zhang*, Hongsheng Lin* and Yuhui Liao*(末位通讯). Emergency Treatment and Photoacoustic Assessment of Spinal Cord Injury Using Reversible Dual-Signal Transform-Based Selenium Antioxidant. Small. 2023, accepted (SCI indexed, IF= 15.153; 化学一区)

7) Zhijin Fan#, Keng Xiao#, Jingyan Lin, Yuhui Liao*(共同通讯) & Xi Huang*. Functionalized DNA Enables Programming Exosomes/Vesicles for Tumor Imaging and Therapy. Small. 2019, 1903761 (SCI indexed, IF= 15.153; 化学一区)

8) Zhaoyan Zhao#, Qingqin Tan#, Jingyan Lin, Zhijin Fan, Keng Xiao, Bing Li, Yuhui Liao*(共同通讯) and Xi Huang*. Cascaded Electrochemiluminescence Signal-Amplifier for Detection of Telomerase Activity from Tumor Cells and Tissues. Theranostics. 2018, 8, 5625-5633. (SCI indexed, IF= 11.600; 医学一区)

9) Yuhui Liao (第一作者), Xiaoming Zhou*, Yu Fu, and Da Xing*. Graphene Oxide as a Bifunctional Material Towards Superior RNA Protection and Extraction. ACS Applied Materials & Interfaces. 2018, 10, 30227-30234. (SCI indexed, IF= 10.383; 工程技术一区)

10) Yuhui Liao (第一作者), Xiaoming Zhou*,Da Xing*. Quantum Dots and Graphene Oxide Fluorescent Switch Based Multivariate Testing Strategy for Reliable Detection of Listeria monocytogenes. ACS Applied Materials & Interfaces. 2014, 6, 9988-9996. (SCI indexed, IF= 10.383; 工程技术一区)